U21 boss Brian Flynn put's his lads up against a host of Premiership youngsters in Stuart Pearce's team. The Welsh lads including Wayne Hennessey, Chris Gunter and David Edwards, the likes of Arsenal's Theo Walcott, Aston Villa's Gabriel Agbonlahor and West Ham's Mark Noble.
There will be no Cardiff City players involved because of the FA Cup Final on Saturday.
"There's no such thing as a friendly against England, no chance," said Flynn. "It will be competitive and it will be everything you want from an international.
"It's a very strong England squad and we are nearly strong as we could be. It's going to be an enticing game.
"It's a mouth-watering prospect for the players because they will be up against quality Premiership players. We will see how much we can match them."
He continued: "Some people have asked if a defeat would knock our confidence going into the Romania game. But I don't think it would.
"I didn't want an easy friendly just to get a result. That's not what we are about, we want the players to develop."
Wales U21: Wayne Hennessey (Wolverhampton Wanderers), Owain Fon Williams (Crewe Alexandra), Neal Eardley (Oldham Athletic), Chris Gunter (Tottenham Hotspur), Joe Jacobson (Bristol Rovers), Lewin Nyatanga (Derby County), Christian Ribeiro (Bristol City), Mike Williams (Wrexham), Grant Basey (Charlton Athletic), Nicky Adams (Bury), Mark Bradley (Walsall), Jack Collison (West Ham United), Marc Williams (Wrexham), David Edwards (Wolverhampton Wanderers), Shaun MacDonald (Swansea City), Ched Evans (Manchester City), Simon Church (Reading), David Cotterill (Wigan Athletic), Craig Davies (Oldham Athletic), Sam Vokes (Bournemouth).
England U21 (from): Joe Hart (Manchester City), Joe Lewis (Peterborough United), Matt Connolly (Queens Park Rangers), Martin Cranie, (Portsmouth), Scott Dann (Coventry City), Danny Fox (Coventry City), Michael Mancienne (Chelsea - ar fenthyg gyda QPR), Ryan Shawcross (Stoke City), Andrew Taylor (Middlesbrough), David Wheater (Middlesbrough), Lee Cattermole (Middlesbrough), Adam Johnson (Middlesbrough), Michael Johnson (Manchester City), Michael Kightly (Wolverhampton Wanderers), Grant Leadbitter (Sunderland), Fabrice Muamba (Birmingham City), Mark Noble (West Ham United), Jamie O'Hara (Tottenham Hotspur), Gabriel Agbonlahor (Aston Villa) Dexter Blackstock (Queens Park Rangers), Theo Walcott (Arsenal).